{"term":{"id":"08186","title":"minimum structural change, principle of","longtitle":"IUPAC Gold Book - minimum structural change, principle of","doi":"10.1351\/goldbook.08186","code":"08186","status":"current","definitions":[{"id":1,"text":"Principle that a chemical reaction is expected to occur with a minimum of bond changes or with a minimum redistribution of electrons (although more complex reaction cascades are also possible).","exams":{"1":"  where the transfer of \\(\\ce{Cl}\\) is accompanied by migration of only one carbon, rather than a more extensive molecular rearrangement involving migration of three methyls."},"sources":["PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 465 (https:\/\/doi.org\/10.1515\/pac-2018-1010)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/08186\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/08186\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/08186\/plain"},"citation":"Citation: 'minimum structural change, principle of' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.08186","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-05-10T12:17:31+00:00"}}