Title: HNCO
Long Title: IUPAC Gold Book - HNCO
DOI: 10.1351/goldbook.08364
Status: current

Definition
Three-dimensional nuclear magnetic resonance spectroscopy for the assignment of protein structure with nitrogen, carbon and hydrogen dimensions.

Note
Magnetization is passed from \(\ce{^{1}H}\) to \(\ce{^{15}N}\) and then selectively to the carbonyl \(\ce{^{13}C}\) via the \(\ce{NH-^{13}CO}\) \(\rm{J}\mbox{-}\rm{coupling}\). Magnetization is then passed back via \(\ce{^{15}N}\) to \(\ce{^{1}H}\) for detection.

Related Term
- Three-dimensional nuclear magnetic resonance spectroscopy: https://goldbook.iupac.org/terms/view/08432

Source
- PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 692 (https://doi.org/10.1515/pac-2019-0203)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/08364/html
- json: https://goldbook.iupac.org/terms/view/08364/json
- xml: https://goldbook.iupac.org/terms/view/08364/xml

Citation: Citation: 'HNCO' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.08364
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Accessed: 2026-07-01T04:28:06+00:00