Title: endocardial cushion
Long Title: IUPAC Gold Book - endocardial cushion
DOI: 10.1351/goldbook.10654
Status: current

Definition
Subset of cells in the primordial tube-like heart that is essential to the development of the ventricular septum and the atrioventricular valves of the heart.

Note
Endocardial cushion defects may cause various types of heart malformation.

Related Terms
- atrioventricular: https://goldbook.iupac.org/terms/view/10440
- malformation: https://goldbook.iupac.org/terms/view/10914
- ventricular septum: https://goldbook.iupac.org/terms/view/11364

Source
- PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 748 (https://doi.org/10.1515/pac-2015-1202)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/10654/html
- json: https://goldbook.iupac.org/terms/view/10654/json
- xml: https://goldbook.iupac.org/terms/view/10654/xml

Citation: Citation: 'endocardial cushion' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10654
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-10T07:54:14+00:00