{"term":{"id":"10858","title":"intermediate filament","longtitle":"IUPAC Gold Book - intermediate filament","doi":"10.1351\/goldbook.10858","code":"10858","status":"current","initialism":"<em>initialism<\/em>: IF","definitions":[{"id":1,"text":"Any of a group of fibrous proteins (including keratin fibres, neurofilaments, desmin, and vimentin) that make up part of the cytoskeleton of most eukaryotic cells; so named because, at about \\(\\pu{10 nm}\\) diameter, they are intermediate in thickness between actin filaments and microtubules.","notes":{"1":"Most types of intermediate filaments are cytoplasmic, but one type, the lamins, is nuclear."},"links":[{"term":"keratin","url":"https:\/\/goldbook.iupac.org\/terms\/view\/10873"}],"sources":["PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 769 (https:\/\/doi.org\/10.1515\/pac-2015-1202)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/10858\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/10858\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/10858\/plain"},"citation":"Citation: 'intermediate filament' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.10858","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-05-09T20:43:46+00:00"}}