Title: osteoclast Long Title: IUPAC Gold Book - osteoclast DOI: 10.1351/goldbook.11050 Status: current Definition Large multinucleate cell that resorbs bone, allowing for the deposition of new bone. Note Osteoclasts secrete enzymes and acids that dissolve the calcium phosphate matrix of old bone tissue. Source - PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 788 (https://doi.org/10.1515/pac-2015-1202) Other Outputs - html: https://goldbook.iupac.org/terms/view/11050/html - json: https://goldbook.iupac.org/terms/view/11050/json - xml: https://goldbook.iupac.org/terms/view/11050/xml Citation: Citation: 'osteoclast' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11050 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-05-24T00:38:23+00:00