Title: primitive node
Long Title: IUPAC Gold Book - primitive node
DOI: 10.1351/goldbook.11129
Status: current

Definition
Group of cells at the anterior end of the primitive streak, involved in secreting chemical signals that regulate differentiation of the germ layers during gastrulation.

Related Terms
- gastrulation: https://goldbook.iupac.org/terms/view/10750
- germ layers: https://goldbook.iupac.org/terms/view/10763
- primitive streak: https://goldbook.iupac.org/terms/view/11131

Source
- PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 796 (https://doi.org/10.1515/pac-2015-1202)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11129/html
- json: https://goldbook.iupac.org/terms/view/11129/json
- xml: https://goldbook.iupac.org/terms/view/11129/xml

Citation: Citation: 'primitive node' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11129
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Accessed: 2026-05-11T03:08:24+00:00