Title: reproductive toxicant
Long Title: IUPAC Gold Book - reproductive toxicant
DOI: 10.1351/goldbook.11173
Status: current

Definition
Agent that interferes with reproductive function, including sexual performance, fertility, and development of the fetus and embryo.

Notes
1) Effects on fertility may include effects on sperm count and sperm viability, oogenesis and ovulation, placental function, lactation, male erectile function, genetic intactness, etc.
2) Effects on development may include effects on embryo viability, fetal growth, morphogenesis, functional integrity, etc.
3) Reproductive toxicants may show long-term effects not detectable before the second or later generations.

Related Terms
- developmental toxicology: https://goldbook.iupac.org/terms/view/10600
- fertility: https://goldbook.iupac.org/terms/view/10710
- fetus: https://goldbook.iupac.org/terms/view/10718
- morphogenesis: https://goldbook.iupac.org/terms/view/10973
- oogenesis: https://goldbook.iupac.org/terms/view/11043
- ovulation: https://goldbook.iupac.org/terms/view/11059
- sperm: https://goldbook.iupac.org/terms/view/11243
- viability: https://goldbook.iupac.org/terms/view/11370

Source
- PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 800 (https://doi.org/10.1515/pac-2015-1202)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11173/html
- json: https://goldbook.iupac.org/terms/view/11173/json
- xml: https://goldbook.iupac.org/terms/view/11173/xml

Citation: Citation: 'reproductive toxicant' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11173
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .
Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-15T11:30:16+00:00