11212 IUPAC Gold Book - sex-determining region Y protein 10.1351/goldbook.11212 11212 current initialism: SRY synonyms: SRY protein, testis-determining factor (TDF) 1 Transcription factor coded by a gene on the Y chromosome that initiates development of the male sex organs (i.e., testicular differentiation) in the embryo. Transcription factor https://goldbook.iupac.org/terms/view/11311 Y chromosome https://goldbook.iupac.org/terms/view/11387 testicular https://goldbook.iupac.org/terms/view/11295 PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 804 (https://doi.org/10.1515/pac-2015-1202) https://goldbook.iupac.org/terms/view/11212/html https://goldbook.iupac.org/terms/view/11212/json https://goldbook.iupac.org/terms/view/11212/plain Citation: 'sex-determining region Y protein' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11212 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-10T23:53:15+00:00