Title: somatomedin
Long Title: IUPAC Gold Book - somatomedin
DOI: 10.1351/goldbook.11229
Status: current

Definition
Any of a group of peptide growth factors produced by the liver following stimulation by somatotropin.

Note
Somatomedin acts directly on cartilage cells to stimulate skeletal growth.

Related Terms
- cartilage: https://goldbook.iupac.org/terms/view/10494
- growth factors: https://goldbook.iupac.org/terms/view/10782
- somatotropin: https://goldbook.iupac.org/terms/view/11230

Source
- PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 806 (https://doi.org/10.1515/pac-2015-1202)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11229/html
- json: https://goldbook.iupac.org/terms/view/11229/json
- xml: https://goldbook.iupac.org/terms/view/11229/xml

Citation: Citation: 'somatomedin' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11229
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-15T10:43:56+00:00