Title: transposition of the great arteries
Long Title: IUPAC Gold Book - transposition of the great arteries
DOI: 10.1351/goldbook.11315
Status: current

Definition
Congenital cardiovascular malformation in which the position of the chief blood vessels of the heart (aorta and pulmonary artery) is reversed.

Note
Survival then depends on a crossflow of blood between the right and left sides of the heart, as through a ventricular septal defect.

Related Terms
- Congenital: https://goldbook.iupac.org/terms/view/10552
- aorta: https://goldbook.iupac.org/terms/view/10416
- conal growth hypothesis: https://goldbook.iupac.org/terms/view/10549
- malformation: https://goldbook.iupac.org/terms/view/10914
- pulmonary artery: https://goldbook.iupac.org/terms/view/11157
- ventricular septal defect: https://goldbook.iupac.org/terms/view/11365

Source
- PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 814 (https://doi.org/10.1515/pac-2015-1202)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11315/html
- json: https://goldbook.iupac.org/terms/view/11315/json
- xml: https://goldbook.iupac.org/terms/view/11315/xml

Citation: Citation: 'transposition of the great arteries' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11315
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-10T06:22:36+00:00