11323 IUPAC Gold Book - trisomy 13 10.1351/goldbook.11323 11323 current synonyms: Patau syndrome, trisomy D 1 Presence of part or all of an extra chromosome 13 from nondisjunction during meiosis. This leads to multiple congenital abnormalities and mental retardation, and is usually fatal in early childhood. Patau syndrome can also occur with an extra partial chromosome 13 resulting from a Robertsonian translocation. Robertsonian translocation https://goldbook.iupac.org/terms/view/11188 congenital abnormalities https://goldbook.iupac.org/terms/view/10554 PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 815 (https://doi.org/10.1515/pac-2015-1202) https://goldbook.iupac.org/terms/view/11323/html https://goldbook.iupac.org/terms/view/11323/json https://goldbook.iupac.org/terms/view/11323/plain Citation: 'trisomy 13' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11323 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-15T05:41:29+00:00