11404 IUPAC Gold Book - 4D quantitative structure-activity relationships 10.1351/goldbook.11404 11404 current initialism: 4D-QSAR 1 A computational model of the quantitative relationship between the target observed independent 1D properties for a set of compounds and the 3D properties of several of their conformations. 1D properties https://goldbook.iupac.org/terms/view/11395 3D properties https://goldbook.iupac.org/terms/view/11400 PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 241 (https://doi.org/10.1515/pac-2012-1204) https://goldbook.iupac.org/terms/view/11404/html https://goldbook.iupac.org/terms/view/11404/json https://goldbook.iupac.org/terms/view/11404/plain Citation: '4D quantitative structure-activity relationships' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11404 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-15T05:40:59+00:00