Title: log P
Long Title: IUPAC Gold Book - log <i>P</i>
DOI: 10.1351/goldbook.11469
Status: current

Definition
The logarithm of the ratio of the concentration of the uncharged form of a compound in a nonpolar phase, traditionally water-saturated octan-1-ol, to that in
 water.

Note
Common algorithms to calculate \(\log P\) are CLOGP and ALOGP.

Source
- PAC, 2016, 88, 239. 'Glossary of terms used in computational drug design, part II (IUPAC Recommendations 2015)' on page 249 (https://doi.org/10.1515/pac-2012-1204)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11469/html
- json: https://goldbook.iupac.org/terms/view/11469/json
- xml: https://goldbook.iupac.org/terms/view/11469/xml

Citation: Citation: 'log <i>P</i>' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11469
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Accessed: 2026-05-15T03:54:29+00:00