11563 IUPAC Gold Book - active avoidance test 10.1351/goldbook.11563 11563 current 1 Fear-motivated associative avoidance test based on presentation of an adverse stimulus (e.g., an electric current) as a source of discomfort, to create an environment from which the animal or subject would prefer to escape. In this test, a mouse or rat learns to associate the occurrence of an aversive event with the presentation of a specific stimulus, and to avoid the event by actively moving to a different location. The number of avoidances (moving to the other location during the stimulus signal), number of non-responses or errors (failing to move to the other location during the trial), and response latency (time between signal onset and response), are used as an index of learning. avoidance test https://goldbook.iupac.org/terms/view/11626 PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 843 (https://doi.org/10.1515/pac-2015-0103) https://goldbook.iupac.org/terms/view/11563/html https://goldbook.iupac.org/terms/view/11563/json https://goldbook.iupac.org/terms/view/11563/plain Citation: 'active avoidance test' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11563 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-24T13:03:11+00:00