Title: demyelination
Long Title: IUPAC Gold Book - demyelination
DOI: 10.1351/goldbook.11707
Status: current

Definition
Destruction of the protective myelin sheath that surrounds nerve fibers, resulting in diminished function and decreased action potential in those nerves.

Related Terms
- myelin sheath: https://goldbook.iupac.org/terms/view/11899
- nerve: https://goldbook.iupac.org/terms/view/11909

Source
- PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 860 (https://doi.org/10.1515/pac-2015-0103)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11707/html
- json: https://goldbook.iupac.org/terms/view/11707/json
- xml: https://goldbook.iupac.org/terms/view/11707/xml

Citation: Citation: 'demyelination' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11707
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-06-30T17:39:36+00:00