Title: inclusion body
Long Title: IUPAC Gold Book - inclusion body
DOI: 10.1351/goldbook.11828
Status: current

Definition
Particle in a cell, detectable under the light microscope.

Note
Inclusion bodies often consist of aggregates of misfolded proteins and are often found in neurodegenerative diseases, such as the β-amyloid plaques in Alzheimer disease.

Related Terms
- Alzheimer disease: https://goldbook.iupac.org/terms/view/11574
- misfolded proteins: https://goldbook.iupac.org/terms/view/11878
- neurodegenerative diseases: https://goldbook.iupac.org/terms/view/11926
- β-amyloid plaques: https://goldbook.iupac.org/terms/view/11581

Source
- PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 875 (https://doi.org/10.1515/pac-2015-0103)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11828/html
- json: https://goldbook.iupac.org/terms/view/11828/json
- xml: https://goldbook.iupac.org/terms/view/11828/xml

Citation: Citation: 'inclusion body' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11828
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-10T11:45:16+00:00