<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>11828</id>
  <title>inclusion body</title>
  <longtitle>IUPAC Gold Book - inclusion body</longtitle>
  <doi>10.1351/goldbook.11828</doi>
  <code>11828</code>
  <status>current</status>
  <definitions>
    <item>
      <id>1</id>
      <text>Particle in a cell, detectable under the light microscope.</text>
      <notes>
        <item>Inclusion bodies often consist of aggregates of misfolded proteins and are often found in neurodegenerative diseases, such as the β-amyloid plaques in Alzheimer disease.</item>
      </notes>
      <links>
        <item>
          <term>Alzheimer disease</term>
          <url>https://goldbook.iupac.org/terms/view/11574</url>
        </item>
        <item>
          <term>misfolded proteins</term>
          <url>https://goldbook.iupac.org/terms/view/11878</url>
        </item>
        <item>
          <term>neurodegenerative diseases</term>
          <url>https://goldbook.iupac.org/terms/view/11926</url>
        </item>
        <item>
          <term>β-amyloid plaques</term>
          <url>https://goldbook.iupac.org/terms/view/11581</url>
        </item>
      </links>
      <sources>
        <item>PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 875 (https://doi.org/10.1515/pac-2015-0103)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/11828/html</html>
    <json>https://goldbook.iupac.org/terms/view/11828/json</json>
    <plain>https://goldbook.iupac.org/terms/view/11828/plain</plain>
  </altoutputs>
  <citation>Citation: 'inclusion body' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11828</citation>
  <license>The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.</license>
  <collection>If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .</collection>
  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-05-10T11:44:59+00:00</accessed>
</term>
