Title: motor neuron disease
Long Title: IUPAC Gold Book - motor neuron disease
DOI: 10.1351/goldbook.11888
Status: current

Definition
Generic term for a heterogeneous group of disorders, all affecting motor neurons in the brain, spinal cord, or both.

Example
Spinal muscle atrophy, amyotrophic lateral sclerosis, progressive bulbar paralysis, and primary lateral sclerosis.

Related Terms
- amyotrophic lateral sclerosis: https://goldbook.iupac.org/terms/view/11583
- brain: https://goldbook.iupac.org/terms/view/11647
- motor neurons: https://goldbook.iupac.org/terms/view/11887

Source
- PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 883 (https://doi.org/10.1515/pac-2015-0103)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/11888/html
- json: https://goldbook.iupac.org/terms/view/11888/json
- xml: https://goldbook.iupac.org/terms/view/11888/xml

Citation: Citation: 'motor neuron disease' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11888
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .
Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-07-26T20:13:39+00:00