<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>11897</id>
  <title>myelin basic protein</title>
  <longtitle>IUPAC Gold Book - myelin basic protein</longtitle>
  <doi>10.1351/goldbook.11897</doi>
  <code>11897</code>
  <status>current</status>
  <definitions>
    <item>
      <id>1</id>
      <text>Major component of myelin, that helps organizing the correct assembly of the lipids and proteins in myelin sheets.</text>
      <notes>
        <item>Absence of myelin basic protein in animals results in seizures.</item>
        <item>Myelin basic protein levels in the cerebrospinal fluid are elevated in various demyelinizing disorders, including multiple sclerosis where autoantibodies against myelin basic protein are believed to play a role.</item>
      </notes>
      <links>
        <item>
          <term>demyelinizing</term>
          <url>https://goldbook.iupac.org/terms/view/11707</url>
        </item>
        <item>
          <term>multiple sclerosis</term>
          <url>https://goldbook.iupac.org/terms/view/11891</url>
        </item>
        <item>
          <term>myelin</term>
          <url>https://goldbook.iupac.org/terms/view/11896</url>
        </item>
      </links>
      <sources>
        <item>PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 884 (https://doi.org/10.1515/pac-2015-0103)</item>
      </sources>
    </item>
  </definitions>
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    <html>https://goldbook.iupac.org/terms/view/11897/html</html>
    <json>https://goldbook.iupac.org/terms/view/11897/json</json>
    <plain>https://goldbook.iupac.org/terms/view/11897/plain</plain>
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  <citation>Citation: 'myelin basic protein' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11897</citation>
  <license>The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.</license>
  <collection>If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .</collection>
  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-06-30T15:48:23+00:00</accessed>
</term>
