neurofibrillary tangle

https://doi.org/10.1351/goldbook.11929
Intracellular accumulation of aggregates of hyperphosphorylated tau protein or paired helical filaments consisting of the tau protein, a microtubule-associated protein that normally stabilizes the cytoskeleton.
Note: Neurofibrillary tangles are characteristically found in neurons of the cerebral cortex of patients with Alzheimer disease.
Source:
PAC, 2015, 87, 841. (IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)) on page 888 [Terms] [Paper]
Citation: 'neurofibrillary tangle' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.11929 RIS BibTex EndNote
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