{"term":{"id":"11998","title":"Parkinson disease","longtitle":"IUPAC Gold Book - Parkinson disease","doi":"10.1351\/goldbook.11998","code":"11998","status":"current","synonym":"<em>synonyms<\/em>: idiopathic parkinsonism, primary parkinsonism","definitions":[{"id":1,"text":"Degenerative disorder of the central nervous system resulting from decreased production of the neurotransmitterdopamine in the basal ganglia (notably the substantia nigra).","notes":{"1":"Characterized by rhythmic muscle tremor, rigidity of movement, and a mask-like face.","2":"Usually idiopathic, although inherited cases occur."},"links":[{"term":"dopamine","url":"https:\/\/goldbook.iupac.org\/terms\/view\/11723"},{"term":"neurotransmitter","url":"https:\/\/goldbook.iupac.org\/terms\/view\/11955"},{"term":"substantia nigra","url":"https:\/\/goldbook.iupac.org\/terms\/view\/12103"},{"term":"tremor","url":"https:\/\/goldbook.iupac.org\/terms\/view\/12149"}],"sources":["PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 895 (https:\/\/doi.org\/10.1515\/pac-2015-0103)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/11998\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/11998\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/11998\/plain"},"citation":"Citation: 'Parkinson disease' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.11998","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-07-24T23:45:50+00:00"}}