analogue

synonym: analog
https://doi.org/10.1351/goldbook.12618
Chemical compound having structural similarity to a reference compound.
Note: Despite the structural similarity, an analogue may display different chemical and/or biological properties, as is often intentionally the case during design and synthesis to optimize either efficacy or ADMET properties within a given series.
See also: analogue-based drug discovery, follow-on drug
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1727 [Terms] [Paper]
Citation: 'analogue' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.12618 RIS BibTex EndNote
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