autoinduction

https://doi.org/10.1351/goldbook.12622
Capacity of a drug to induce enzymes that mediate its own metabolism.
Note: This often results in lower, often sub-therapeutic, drug exposure on prolonged or multiple dosing.
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1728 [Terms] [Paper]