fast follower

https://doi.org/10.1351/goldbook.12655
Compound selected as a rapid successor to a lead drug candidate.
Note: Fast followers usually possess a marked increase in one or more pharmacological/pharmaceutical characteristics such as potency, efficacy, therapeutic index, or physicochemical parameters (e.g., solubility).
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1734 [Terms] [Paper]