Generation of additional compound sets that contain chemical motifs and
scaffolds that have activity in the primary screen.
Note: This methodology permits the identification of additional
hits and new
scaffolds and develops structure-activity relationships around existing
hits.
Source: PAC, 2013,
85, 1725. (
Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1737 [
Terms] [
Paper]