orphan drug

https://doi.org/10.1351/goldbook.12699
Pharmaceutical agent that has been approved specifically to treat a rare and commercially unfavourable medical condition.
See also: orphan disease
Source:
PAC, 2013, 85, 1725. (Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)) on page 1744 [Terms] [Paper]