Title: acute lymphoblastic leukemia
Long Title: IUPAC Gold Book - acute lymphoblastic leukemia
DOI: 10.1351/goldbook.12837
Status: current

Definition
Highly aggressive, undifferentiated form of lymphoid malignancy derived from a progenitor cell that is thought to be able to give rise to both T- and B-cell lineages.

Note
Most of these leukemias show partial differentiation toward the B-cell lineage (so-called B-ALL) whereas a minority show features of T cells (T-ALL).

Related Terms
- B-cell: https://goldbook.iupac.org/terms/view/12937
- T-: https://goldbook.iupac.org/terms/view/13724
- leukemias: https://goldbook.iupac.org/terms/view/13378

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1117 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12837/html
- json: https://goldbook.iupac.org/terms/view/12837/json
- xml: https://goldbook.iupac.org/terms/view/12837/xml

Citation: Citation: 'acute lymphoblastic leukemia' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12837
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-06-28T23:26:58+00:00