{"term":{"id":"12843","title":"adaptive immune response","longtitle":"IUPAC Gold Book - adaptive immune response","doi":"10.1351\/goldbook.12843","code":"12843","status":"current","definitions":[{"id":1,"text":"Immune response based on the principle of clonal recognition, such that upon first exposure to an antigen, primed lymphocytes either differentiate into immune effector cells or form an expanded pool of memory cells that respond to secondary exposure to the same antigen by mounting an amplified and more rapid response.","notes":{"1":"The response may be classified as cellular (T cell-mediated) or humoral (antibody-dependent)."},"links":[{"term":"T cell","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13724"},{"term":"humoral","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13234"},{"term":"lymphocytes","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13399"},{"term":"memory cells","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13452"}],"sources":["PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1117 (https:\/\/doi.org\/10.1351\/PAC-REC-11-06-03)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/12843\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/12843\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/12843\/plain"},"citation":"Citation: 'adaptive immune response' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.12843","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-05-10T12:47:24+00:00"}}