Title: adhesion molecule
Long Title: IUPAC Gold Book - adhesion molecule
DOI: 10.1351/goldbook.12848
Status: current

Definition
Molecule belonging mainly to the immunoglobulins, integrin superfamily (e.g., LFA-1, ICAM-1) or selectins, expressed on the cell membrane of various cells including those of the immune system. Interaction of adhesion molecules with each other as receptor and corresponding ligand facilitates cooperation (cross-talk) of cells, signal transduction, and information transfer between cells.

Related Terms
- immune system: https://goldbook.iupac.org/terms/view/13271
- selectins: https://goldbook.iupac.org/terms/view/13667
- superfamily: https://goldbook.iupac.org/terms/view/13700

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1118 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12848/html
- json: https://goldbook.iupac.org/terms/view/12848/json
- xml: https://goldbook.iupac.org/terms/view/12848/xml

Citation: Citation: 'adhesion molecule' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12848
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Accessed: 2026-05-10T05:09:38+00:00