12856 IUPAC Gold Book - allelic exclusion 10.1351/goldbook.12856 12856 current 1 Phenomenon whereby, following successful rearrangement of one allele of an antigen receptor gene, rearrangement of the other parental allele is suppressed, thereby ensuring each lymphocyte expresses only a single specificity of antigen receptor. This does not occur for \(\upalpha\) chains in T lymphocytes. T lymphocytes https://goldbook.iupac.org/terms/view/13724 antigen receptor https://goldbook.iupac.org/terms/view/12891 lymphocyte https://goldbook.iupac.org/terms/view/13399 PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1120 (https://doi.org/10.1351/PAC-REC-11-06-03) https://goldbook.iupac.org/terms/view/12856/html https://goldbook.iupac.org/terms/view/12856/json https://goldbook.iupac.org/terms/view/12856/plain Citation: 'allelic exclusion' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12856 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-07-26T04:27:37+00:00