Title: anaphylaxis
Long Title: IUPAC Gold Book - anaphylaxis
DOI: 10.1351/goldbook.12874
Status: current

Definition
Life-threatening type I hypersensitivity allergic reaction occurring in a person or animal exposed to an antigen or hapten to which they have previously been sensitized.

Note
Consequences of the reaction may include angioedema, vascular collapse, shock, and respiratory distress.

Related Terms
- allergic reaction: https://goldbook.iupac.org/terms/view/12859
- angioedema: https://goldbook.iupac.org/terms/view/12876
- shock: https://goldbook.iupac.org/terms/view/12871
- type I hypersensitivity: https://goldbook.iupac.org/terms/view/13255

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1122 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12874/html
- json: https://goldbook.iupac.org/terms/view/12874/json
- xml: https://goldbook.iupac.org/terms/view/12874/xml

Citation: Citation: 'anaphylaxis' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12874
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .
Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-14T12:43:46+00:00