Title: B-lymphocyte-induced maturation protein 1
Long Title: IUPAC Gold Book - B-lymphocyte-induced maturation protein 1
DOI: 10.1351/goldbook.12939
Status: current

Definition
Transcriptional repressor in B cells, that switches off genes required for B cell proliferation in the germinal center, and for class switching and affinity maturation.

Note
B cells in which BLIMP-1 is induced become plasma cells.

Related Terms
- B cells: https://goldbook.iupac.org/terms/view/12937
- affinity maturation: https://goldbook.iupac.org/terms/view/12854
- class switching: https://goldbook.iupac.org/terms/view/13010
- germinal center: https://goldbook.iupac.org/terms/view/13172
- plasma cells: https://goldbook.iupac.org/terms/view/13576

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1133 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12939/html
- json: https://goldbook.iupac.org/terms/view/12939/json
- xml: https://goldbook.iupac.org/terms/view/12939/xml

Citation: Citation: 'B-lymphocyte-induced maturation protein 1' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12939
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Accessed: 2026-05-14T14:53:41+00:00