Title: bispecific antibody
Long Title: IUPAC Gold Book - bispecific antibody
DOI: 10.1351/goldbook.12951
Status: current

Definition
Artificially produced hybrid antibody in which each of the two antigen-binding arms is specific for a different antigenic epitope. Such antibodies, which can be produced either by chemical cross-linkage or by recombinant DNA techniques, can be used to link together two different antigens or cells, e.g., a cytotoxic T lymphocyte and a tumor cell.

Related Term
- cytotoxic T lymphocyte: https://goldbook.iupac.org/terms/view/13072

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1134 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/12951/html
- json: https://goldbook.iupac.org/terms/view/12951/json
- xml: https://goldbook.iupac.org/terms/view/12951/xml

Citation: Citation: 'bispecific antibody' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12951
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Accessed: 2026-07-23T16:04:15+00:00