blood–placenta barrier

https://doi.org/10.1351/goldbook.12957
Physiological interface between maternal and fetal blood circulations that filters out some substances that could harm the fetus while favoring the passage of others such as nutrients.
Notes:
  1. Many fat-soluble substances such as alcohol are not filtered out, and several types of virus can also cross this barrier.
  2. The effectiveness of the interface as a barrier varies with species and different forms of placentation.
  3. Immunoglobulin G (IgG) antibodies are specifically transported across the barrier and reach the same levels in the newborn, as in the mother.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1135 [Terms] [Paper]
Citation: 'blood–placenta barrier' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.12957 RIS BibTex EndNote
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