<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>12968</id>
  <title>bystander effect</title>
  <longtitle>IUPAC Gold Book - bystander effect</longtitle>
  <doi>10.1351/goldbook.12968</doi>
  <code>12968</code>
  <status>current</status>
  <definitions>
    <item>
      <id>1</id>
      <text>Positive or negative effect on the immune system seen after exposure to certain drugs, radiation, and other agents, induced by non-immune mechanisms.</text>
      <contexts/>
      <links>
        <item>
          <term>bystander suppression</term>
          <url>https://goldbook.iupac.org/terms/view/12969</url>
        </item>
        <item>
          <term>immune system</term>
          <url>https://goldbook.iupac.org/terms/view/13271</url>
        </item>
      </links>
      <sources>
        <item>PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1137 (https://doi.org/10.1351/PAC-REC-11-06-03)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/12968/html</html>
    <json>https://goldbook.iupac.org/terms/view/12968/json</json>
    <plain>https://goldbook.iupac.org/terms/view/12968/plain</plain>
  </altoutputs>
  <citation>Citation: 'bystander effect' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12968</citation>
  <license>The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.</license>
  <collection>If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .</collection>
  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-07-23T11:14:20+00:00</accessed>
</term>
