Title: chronic allergic inflammation
Long Title: IUPAC Gold Book - chronic allergic inflammation
DOI: 10.1351/goldbook.13005
Status: current

Definition
Disease of airways, skin, eyes and other organs, resulting from repeated or continuous exposure to an allergen and involving immunoglobulin E (IgE) formation, IgE-induced histamine-release from mast cells, liberation of mediators such as cytokines and prostaglandins, and local inflammation characterized by infiltrating leucocytes; it results in augmented susceptibility to the allergen.

Related Terms
- allergen: https://goldbook.iupac.org/terms/view/12857
- cytokines: https://goldbook.iupac.org/terms/view/13065
- immunoglobulin E (IgE): https://goldbook.iupac.org/terms/view/13288
- leucocytes: https://goldbook.iupac.org/terms/view/13379
- mast cells: https://goldbook.iupac.org/terms/view/13442

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1143 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13005/html
- json: https://goldbook.iupac.org/terms/view/13005/json
- xml: https://goldbook.iupac.org/terms/view/13005/xml

Citation: Citation: 'chronic allergic inflammation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13005
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-06-28T23:25:48+00:00