classical pathway

of complement activation
https://doi.org/10.1351/goldbook.13011
Activation pathway involving complement components C1, C2, and C4 which, following fixation of C1q, e.g., by antigen-antibody complexes, produces the classical pathway C3 convertase C4b2a.
See also: alternative pathway (of complement activation)
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1144 [Terms] [Paper]
Citation: 'classical pathway' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13011 RIS BibTex EndNote
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