13065 IUPAC Gold Book - cytokine 10.1351/goldbook.13065 13065 current 1 Any of a group of soluble small proteins released from a variety of cells, typically of the immune system, that affect cell behavior in an autocrine or paracrine fashion. Cytokines produced by lymphocytes are known as lymphokines; those produced by monocytes are called monokines. Other types of cytokines include chemokines, growth factors, colony-stimulating factors (CSFs), transforming growth factors, interferons, interleukins, and tumor necrosis factors. autocrine https://goldbook.iupac.org/terms/view/12916 colony-stimulating factors (CSFs) https://goldbook.iupac.org/terms/view/13024 immune system https://goldbook.iupac.org/terms/view/13271 lymphocytes https://goldbook.iupac.org/terms/view/13399 lymphokines https://goldbook.iupac.org/terms/view/13415 monocytes https://goldbook.iupac.org/terms/view/13467 monokines https://goldbook.iupac.org/terms/view/13468 transforming growth factors https://goldbook.iupac.org/terms/view/13752 tumor necrosis factors https://goldbook.iupac.org/terms/view/13762 PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1153 (https://doi.org/10.1351/PAC-REC-11-06-03) https://goldbook.iupac.org/terms/view/13065/html https://goldbook.iupac.org/terms/view/13065/json https://goldbook.iupac.org/terms/view/13065/plain Citation: 'cytokine' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13065 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-06-28T13:28:45+00:00