{"term":{"id":"13066","title":"cytokine capture assay","longtitle":"IUPAC Gold Book - cytokine capture assay","doi":"10.1351\/goldbook.13066","code":"13066","status":"current","synonym":"<em>synonym<\/em>: <i>in vivo<\/i> cytokine capture assay (IVCCA)","definitions":[{"id":1,"text":"Method to detect cytokine release by injecting an animal with a neutralizing biotinylated antibody to the cytokine, which inhibits its utilization and allows its accumulation in the blood. Recovered cytokineantibody complexes are then measured in an enzyme-linked immunosorbent assay (ELISA) with an antibody to a second epitope on the cytokine.","links":[{"term":"cytokine","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13065"},{"term":"enzyme-linked immunosorbent assay (ELISA)","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13115"}],"sources":["PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1153 (https:\/\/doi.org\/10.1351\/PAC-REC-11-06-03)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/13066\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/13066\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/13066\/plain"},"citation":"Citation: 'cytokine capture assay' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.13066","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-06-28T14:43:18+00:00"}}