Title: humoral immunity Long Title: IUPAC Gold Book - humoral immunity DOI: 10.1351/goldbook.13236 Status: current Definition Specific immune response that is mediated primarily by humoral factors circulating in solution in the blood plasma and lymph (i.e., antibodies and complement). Note The induction of the humoral immune response generally requires the cooperation of cellular immune mechanisms. Related Term - humoral immune response: https://goldbook.iupac.org/terms/view/13235 Source - PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1179 (https://doi.org/10.1351/PAC-REC-11-06-03) Other Outputs - html: https://goldbook.iupac.org/terms/view/13236/html - json: https://goldbook.iupac.org/terms/view/13236/json - xml: https://goldbook.iupac.org/terms/view/13236/xml Citation: Citation: 'humoral immunity' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13236 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-05-14T03:35:29+00:00