immunoreceptor tyrosine-based inhibitory motif

initialism: ITIM
https://doi.org/10.1351/goldbook.13314
Consensus sequence present in the cytoplasmic domains of certain cell surface molecules [e.g., Fc \(\upgamma\) RIIB, inhibitory natural killer (NK) cell receptors] and which mediates inhibitory signals.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1191 [Terms] [Paper]
Citation: 'immunoreceptor tyrosine-based inhibitory motif' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13314 RIS BibTex EndNote
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