immunostimulating complex

initialism: ISCOM
https://doi.org/10.1351/goldbook.13317
Immunological adjuvant composed of saponin, cholesterol, phospholipid, and an immunogen, usually protein.
Note: The adjuvant was originally designed to form a vaccine delivery system that combined certain aspects of virus particles such as their size and orientation of surface proteins, with the powerful immunostimulatory activity of saponins.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1191 [Terms] [Paper]
Citation: 'immunostimulating complex' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13317 RIS BibTex EndNote
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