Enzyme catalyzing the initial rate-limiting step of
tryptophan degradation.
Note: Tryptophan is required for
T-cell proliferation. Local degradation of tryptophan thus modulates
T-cell activity.
Source: PAC, 2012,
84, 1113. (
IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1193 [
Terms] [
Paper]