linear epitope

synonym: continuous epitope
https://doi.org/10.1351/goldbook.13388
Antigenic determinant that is contiguous in the amino acid sequence of a protein and therefore does not require the protein to be folded into its native conformation for antibody to bind.
Note: The epitopes detected by T cells are continuous.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1202 [Terms] [Paper]
Citation: 'linear epitope' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13388 RIS BibTex EndNote
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