linked recognition

https://doi.org/10.1351/goldbook.13389
Requirement for a helper T lymphocyte (Th) and B lymphocyte to interact with separate but physically linked epitopes in the same antigen, in order for an immune response to a thymus-dependent (TD) antigen.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1202 [Terms] [Paper]