Title: mammalian target of rapamycin
Long Title: IUPAC Gold Book - mammalian target of rapamycin
DOI: 10.1351/goldbook.13436
Status: current

Definition
Intracellular signaling molecule (phosphoinositide-3-kinase) involved in control of cell growth, whose activity is negatively influenced by the immunosuppressive drug rapamycin.

Related Term
- immunosuppressive: https://goldbook.iupac.org/terms/view/13320

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1209 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13436/html
- json: https://goldbook.iupac.org/terms/view/13436/json
- xml: https://goldbook.iupac.org/terms/view/13436/xml

Citation: Citation: 'mammalian target of rapamycin' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13436
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Accessed: 2026-05-10T20:02:06+00:00