mitogen-activated protein kinase

initialism: MAPK
https://doi.org/10.1351/goldbook.13462
Member of a kinase network in which "upstream" kinases activate "downstream" kinases that, in response to phosphorylation, translocate to the nucleus and activate transcription factors.
Note: These include the extracellular regulated kinases (Erk), stress-activated protein kinase (SAPK or p38), and the kinase of the c-jun oncoprotein (JNK).
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1213 [Terms] [Paper]
Citation: 'mitogen-activated protein kinase' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13462 RIS BibTex EndNote
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