Title: mucosal addressin cell adhesion molecule-1
Long Title: IUPAC Gold Book - mucosal addressin cell adhesion molecule-1
DOI: 10.1351/goldbook.13475
Status: current

Definition
Protein involved in trafficking of lymphocytes to mucosal endothelium.

Note
Expression of MAdCAM-1 is induced in the murine endothelial cell line bEnd.3 by tumor necrosis factor α (TNF-α), interleukin (IL)-1, and bacterial lipopolysaccharide (LPS).

Related Terms
- interleukin (IL): https://goldbook.iupac.org/terms/view/13338
- lymphocytes: https://goldbook.iupac.org/terms/view/13399
- mucosal: https://goldbook.iupac.org/terms/view/13473
- tumor necrosis factor α (TNF-α): https://goldbook.iupac.org/terms/view/13762

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1215 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13475/html
- json: https://goldbook.iupac.org/terms/view/13475/json
- xml: https://goldbook.iupac.org/terms/view/13475/xml

Citation: Citation: 'mucosal addressin cell adhesion molecule-1' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13475
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Accessed: 2026-07-24T10:56:57+00:00