{"term":{"id":"13500","title":"natural killer cell activity assay","longtitle":"IUPAC Gold Book - natural killer cell activity assay","doi":"10.1351\/goldbook.13500","code":"13500","status":"current","definitions":[{"id":1,"text":"Immunotoxicity test in which lymphoid tissue or blood that has been treated with a test compound is co-incubated with target cells. The cytotoxic effect on target cells is measured, e.g., with the chromium release assay. It is used under circumstances where differences from untreated cells are attributed to natural killer (NK) cell activity.","links":[{"term":"chromium release assay","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13004"},{"term":"lymphoid tissue","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13414"},{"term":"natural killer (NK) cell","url":"https:\/\/goldbook.iupac.org\/terms\/view\/13499"}],"sources":["PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1219 (https:\/\/doi.org\/10.1351\/PAC-REC-11-06-03)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/13500\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/13500\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/13500\/plain"},"citation":"Citation: 'natural killer cell activity assay' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.13500","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-06-30T07:32:39+00:00"}}