Title: Philadelphia chromosome
Long Title: IUPAC Gold Book - Philadelphia chromosome
DOI: 10.1351/goldbook.13565
Status: current

Definition
Chromosome resulting from a reciprocal translocation between human chromosomes 9 and 22, most commonly associated with chronic myelogenous leukemia (CML).

Related Terms
- ABL oncogene: https://goldbook.iupac.org/terms/view/12827
- chronic myelogenous leukemia (CML): https://goldbook.iupac.org/terms/view/13008

Source
- PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1228 (https://doi.org/10.1351/PAC-REC-11-06-03)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/13565/html
- json: https://goldbook.iupac.org/terms/view/13565/json
- xml: https://goldbook.iupac.org/terms/view/13565/xml

Citation: Citation: 'Philadelphia chromosome' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13565
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-05-10T15:59:54+00:00